{"id":8833,"date":"2024-12-03T08:32:41","date_gmt":"2024-12-03T07:32:41","guid":{"rendered":"https:\/\/savir-center.com\/?page_id=8833"},"modified":"2024-12-03T12:10:52","modified_gmt":"2024-12-03T11:10:52","slug":"wolfram-syndrome","status":"publish","type":"page","link":"https:\/\/savir-center.com\/en\/wolfram-syndrome\/","title":{"rendered":"Wolfram syndrome"},"content":{"rendered":"\n<div class=\"wp-block-cover alignment-full\" style=\"min-height:400px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\" style=\"background-color:#5b4117\"><\/span><img decoding=\"async\" width=\"1400\" height=\"600\" class=\"wp-block-cover__image-background wp-image-8818\" alt=\"Optikusatrophie\" src=\"https:\/\/savir-center.com\/wp-content\/uploads\/optikusatrophie-1.webp\" data-object-fit=\"cover\" srcset=\"https:\/\/savir-center.com\/wp-content\/uploads\/optikusatrophie-1.webp 1400w, https:\/\/savir-center.com\/wp-content\/uploads\/optikusatrophie-1-300x129.webp 300w, https:\/\/savir-center.com\/wp-content\/uploads\/optikusatrophie-1-1024x439.webp 1024w, https:\/\/savir-center.com\/wp-content\/uploads\/optikusatrophie-1-768x329.webp 768w\" sizes=\"(max-width: 1400px) 100vw, 1400px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center text-shadow-white has-white-color has-text-color has-link-color has-x-large-font-size wp-elements-f5be6733c5870302494a5d8334e9b00d\" id=\"--amblyopia--\" style=\"line-height:1\"><strong><strong>Wolfram Syndrome<\/strong><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center text-shadow-white has-white-color has-text-color has-link-color has-medium-font-size wp-elements-ba9672045c65bc8a302c5db8597a89a2\" id=\"--all-info-about-amblyopia--\" style=\"line-height:1\"><strong><strong>All info about Wolfram Syndrome<\/strong><\/strong><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><p>Table of Contents<\/p><nav><ul><li><a href=\"#the-two-types-of-wolfram-syndrome-and-their-symptoms\">The two types of Wolfram Syndrome and their symptoms<\/a><\/li><li><a href=\"#causes-of-wolfram-syndrome\">Causes of Wolfram Syndrome<\/a><\/li><li><a href=\"#diagnosis-of-wolfram-syndrome\">Diagnosis of Wolfram Syndrome<\/a><\/li><li><a href=\"#treatment-of-wolfram-syndrome\">Treatment of Wolfram Syndrome<\/a><\/li><li><a href=\"#savir-therapy-for-wolfram-syndrome\">SAVIR Therapy for Wolfram Syndrome<\/a><\/li><li><a href=\"#risks-and-side-effects-of-savir-therapy-for-optic-atrophy\">Risks and side effects of SAVIR Therapy for optic atrophy<\/a><\/li><li><a href=\"#am-i-a-candidate\">Am I a Candidate?<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center\" id=\"what-is-optic-atrophy\">What is Wolfram Syndrome (WS)?<\/h1>\n\n\n\n<p>This extremely rare, genetically determined disease was first described in 1938 by Dr. Hans Wolfram and named after him. Other terms describe the symptoms of the disease: arginine-vasopressin deficiency, diabetes mellitus, optic atrophy, hearing loss syndrome, or DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy, deafness syndrome).<\/p>\n\n\n\n<p>Wolfram Syndrome is inherited in an autosomal recessive manner and occurs in only one in 160,000 to one in 770,000 cases\u2014sources vary. The disease often manifests in childhood and can lead to premature death due to respiratory arrest.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<figure class=\"wp-block-image is-resized size-150x150\"><img decoding=\"async\" src=\"https:\/\/savir-center.com\/wp-content\/uploads\/elementor\/thumbs\/Prof-Bernhard-Sabel-pjygsv24v2wx7hiae5x3qplk2lv6urf4wz9gm53azg.webp\" alt=\"Prof. Bernhard Sabel\" style=\"object-fit:cover;width:150px;height:150px\" title=\"Prof-Bernhard-Sabel\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:75%\">\n<p class=\"has-black-color has-text-color has-link-color wp-elements-0b80098a171467154264aa5a3687b660\" id=\"--prof-dr-bernhard-sabel--\" style=\"font-size:28px\"><em><a href=\"https:\/\/en.wikipedia.org\/wiki\/Bernhard_Sabel\" target=\"_blank\" data-type=\"link\" data-id=\"https:\/\/en.wikipedia.org\/wiki\/Bernhard_Sabel\" rel=\"noreferrer noopener\">Prof. Dr. Bernhard Sabel<\/a><\/em><\/p>\n\n\n\n<p class=\"has-small-font-size\" id=\"-\u201cthe-optimization-of-residual-vision-is-a-holistic-complement-to-ophthalmological-care-such-as-eye-drops-or-surgeries-we-continue-where-ophthalmology-stops-we-combine-conventional-medical-science-with-new-findings-from-modern-brain-research-and-traditional-medicine-methods\u201d-\"><em>\u201cThe optimization of residual vision is a holistic complement to ophthalmological care such as eye drops or surgeries. We continue where ophthalmology stops. We combine conventional medical science with new findings from modern brain research and traditional medicine methods.\u201d<\/em><\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"the-two-types-of-wolfram-syndrome-and-their-symptoms\">The two types of Wolfram Syndrome and their symptoms<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>Type 1, this type results from a mutation in the WFS1 gene. The disease typically presents early with insulin-dependent diabetes mellitus and optic atrophy. Patients lose visual acuity and the ability to perceive colors. Other associated conditions may include glaucoma, abnormal pupillary light reflexes, cataracts, or retinopathy.<\/p>\n\n\n\n<p>Half of those affected also develop diabetes insipidus, in which the body can no longer adequately concentrate urine due to a lack of the hormone vasopressin.<\/p>\n\n\n\n<p>Additional features of WS1 may include urinary tract abnormalities and neurological disorders such as ataxia, epilepsy, depression, or cognitive impairment.<\/p>\n\n\n\n<p>The disease becomes life-threatening when respiratory issues such as apnea occur. Gastrointestinal disorders are also common, often leading to pneumonia if vomited or regurgitated stomach contents enter the lungs.<\/p>\n\n\n\n<p>Type 2, This type is caused by mutations in the CISD2 gene and presents with symptoms similar to WS1 but does not include diabetes insipidus.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"causes-of-wolfram-syndrome\">Causes of Wolfram Syndrome<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>Mutations in the WFS1 or CISD2 genes cause the disease, which is inherited in an autosomal recessive manner. At-risk couples carrying mutations in these genes should seek genetic counseling.<\/p>\n\n\n\n<p>Although genetic changes are the cause of the disease, it\u2019s important to note that a genetic defect is not the sole reason for vision impairment. Genes are not always constantly active; they can be turned on and off by the body (known as epigenetics). Furthermore, other factors, such as excessive mental stress or insufficient daily fluid intake (less than 2 liters), can exacerbate vision loss in addition to genetic mutations.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"diagnosis-of-wolfram-syndrome\">Diagnosis of Wolfram Syndrome<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>Once juvenile diabetes and <a href=\"https:\/\/savir-center.com\/en\/optic-atrophy\/\" data-type=\"page\" data-id=\"8811\">optic atrophy<\/a> are identified, family history and\/or genetic screening are conducted. MRI can also detect brain atrophy, particularly in the cerebellum, spinal cord, and pons.<\/p>\n\n\n\n<p>If family gene mutations are known, prenatal diagnosis is now also possible.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"treatment-of-wolfram-syndrome\">Treatment of Wolfram Syndrome<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>There is no causal therapy, treatment must be symptomatic. Since the identified gene effect indicates which diseases to expect, regular follow-ups and early treatments are essential. Diabetes mellitus, diabetes insipidus, respiratory disorders, and urinary tract diseases require particular attention. Expected psychiatric symptoms, such as depression, should not be overlooked.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"savir-therapy-for-wolfram-syndrome\">SAVIR Therapy for Wolfram Syndrome<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>Optic atrophy, a key symptom of Wolfram Syndrome, can be improved with SAVIR therapy. A clinical study on optic atrophy has confirmed that small microcurrent impulses activate the brain, enabling it to process the remaining optical stimuli more effectively.<\/p>\n\n\n\n<p>This alternating current therapy is particularly effective for patients suffering from glaucoma. <a href=\"https:\/\/savir-center.com\/en\/glaucoma-treatment\/\" data-type=\"page\" data-id=\"4648\">Read more here<\/a>.<\/p>\n\n\n\n<p>In conventional medicine, damage to the optic nerve or brain is considered irreversible. However, even when the optic nerve is already damaged, patients&#8217; vision can be improved with SAVIR therapy. A clinical study on visual impairments confirmed this. Small microcurrent impulses activate inactive nerve cells in the retina, optic nerve, and brain. These inactive nerve cells can survive for a long time (&#8220;dormant&#8221;) because they receive enough oxygen (energy) to survive but not enough to process visual signals. When these silent nerve cells are reactivated by SAVIR therapy, optical stimuli can once again be processed more effectively. This alternating current treatment can significantly enhance vision, allowing patients to see better, even though the genetic damage to the nerve cells cannot be repaired. SAVIR therapy does not address the &#8220;primary damage&#8221; (genetic defect) but rather the secondary damage (dormant cells).<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-14cf5ab5 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<h2 class=\"wp-block-heading has-text-align-right\" id=\"risks-and-side-effects-of-savir-therapy-for-optic-atrophy\">Risks and side effects of SAVIR Therapy for optic atrophy<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<p>To date, no risks or side effects of SAVIR therapy have been observed in thousands of treated patients, including the few with Wolfram Syndrome. The electrical impulses are so weak that they are barely noticeable on the skin. Patients may occasionally experience brief light flashes with their eyes closed during treatment, which are to be expected.<\/p>\n\n\n\n<p>The electrical impulses are also significantly weaker than those of a pacemaker.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignment-full has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"has-text-align-center block-patients-say wp-embed-aspect-16-9 wp-has-aspect-ratio has-link-color wp-elements-8852a0844d7d5c88283097c4e6de6374\" id=\"-was-patienten-sagen-\" style=\"margin-top:var(--wp--preset--spacing--60);margin-right:var(--wp--preset--spacing--40);margin-bottom:var(--wp--preset--spacing--60);margin-left:var(--wp--preset--spacing--40);font-size:45px\"><a href=\"https:\/\/savir-center.com\/testimonials\/\" target=\"_blank\" rel=\"noopener\"><\/a><a href=\"https:\/\/savir-center.com\/testimonials\/\" target=\"_blank\" rel=\"noreferrer noopener\">What our patients say<\/a><\/p>\n\n\n\n<div class=\"wp-block-columns block-patients-say wp-embed-aspect-16-9 wp-has-aspect-ratio is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n <div class=\"brlbs-cmpnt-container brlbs-cmpnt-content-blocker brlbs-cmpnt-with-individual-styles\" data-borlabs-cookie-content-blocker-id=\"youtube-content-blocker\" data-borlabs-cookie-content=\"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\"><div class=\"brlbs-cmpnt-cb-preset-c brlbs-cmpnt-cb-youtube\"> <div class=\"brlbs-cmpnt-cb-thumbnail\" style=\"background-image: url('https:\/\/savir-center.com\/wp-content\/uploads\/borlabs-cookie\/1\/yt_zH5dHcKNPH0_hqdefault.jpg')\"><\/div> <div class=\"brlbs-cmpnt-cb-main\"> <div class=\"brlbs-cmpnt-cb-play-button\"><\/div> <div class=\"brlbs-cmpnt-cb-content\"> <p class=\"brlbs-cmpnt-cb-description\">You are currently viewing a placeholder content from <strong>YouTube<\/strong>. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.<\/p> <a class=\"brlbs-cmpnt-cb-provider-toggle\" href=\"#\" data-borlabs-cookie-show-provider-information role=\"button\">More Information<\/a> <\/div> <div class=\"brlbs-cmpnt-cb-buttons\"> <a class=\"brlbs-cmpnt-cb-btn\" href=\"#\" data-borlabs-cookie-unblock role=\"button\">Unblock content<\/a> <a class=\"brlbs-cmpnt-cb-btn\" href=\"#\" data-borlabs-cookie-accept-service role=\"button\" style=\"display: inherit\">Accept required service and unblock content<\/a> <\/div> <\/div> <\/div><\/div>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p id=\"unsere-patienten-kommen-aus-ganz-deutschland-und-vielen-l\u00e4ndern-weltweit-zu-uns-nach-magdeburg--z-b-aus-\u00f6sterreich-italien-frankreich-polen-schweiz-malta-t\u00fcrkei-usa-kanada-dubaivereinigte-arabische-emirate-russland-ukraine-vietnam-china-neuseeland-australien\" style=\"margin-top:var(--wp--preset--spacing--30);margin-right:var(--wp--preset--spacing--30);margin-bottom:var(--wp--preset--spacing--30);margin-left:var(--wp--preset--spacing--30)\">Our patients come to us in Magdeburg from all over Germany and many countries worldwide: e.g. from Austria, Italy, France, Poland, Switzerland Malta, Turkey, USA, Canada, Dubai\/United Arab Emirates, Russia, Ukraine, Vietnam, China, New Zealand, Australia.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-2f773bf9 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/savir-center.com\/wp-content\/uploads\/savir_unterzeile_positiv-0-130-145-1.svg\" alt=\"Logo Sabel Vision Restauration Center\" class=\"wp-image-1296\"\/><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button btn-scale\"><a class=\"wp-block-button__link has-white-color has-text-color has-background wp-element-button\" href=\"https:\/\/savir-center.com\/en\/contact\/\" style=\"border-radius:5px;background-color:#dc5049\">Free Consultation<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n<\/div>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer wp-embed-aspect-16-9 wp-has-aspect-ratio\"><\/div>\n\n\n\n<div class=\"wp-block-group alignment-full has-white-color has-text-color has-background has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-ddcf2457 wp-block-group-is-layout-constrained\" style=\"background-color:#008291;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-columns alignment-full-font is-layout-flex wp-container-core-columns-is-layout-d7d455e7 wp-block-columns-is-layout-flex\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center has-medium-font-size\">Worldwide Unique, Holistic Therapy for Optic Nerve Damage<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-group is-vertical is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-d7b04dc7 wp-block-group-is-layout-flex\">\n<p class=\"has-text-align-center count-30 has-text-color\" style=\"color:#db4139;font-size:69px\">0<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size\">Years of Research Leadership<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center has-medium-font-size\">Years of Experience and Success in Treating Patients<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer wp-embed-aspect-16-9 wp-has-aspect-ratio\"><\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"ist-die-savir-therapie-f\u00fcr-mich-geeignet\" style=\"margin-top:var(--wp--preset--spacing--50);margin-right:var(--wp--preset--spacing--50);margin-bottom:var(--wp--preset--spacing--50);margin-left:var(--wp--preset--spacing--50);font-size:32px;font-style:normal;font-weight:500\">Am I a Candidate?<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:20%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:60%\">\n<div class=\"wp-block-buttons has-custom-font-size btn-read-more invert has-medium-font-size is-content-justification-center is-nowrap is-layout-flex wp-container-core-buttons-is-layout-f28c712a wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-100 has-custom-font-size is-style-fill\" style=\"font-size:24px\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-text-align-center wp-element-button\" href=\"https:\/\/savir-center.com\/en\/test-is-the-treatment-suitable-for-me\/\" style=\"border-radius:15px;background-color:#008291;padding-top:var(--wp--preset--spacing--50);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50);padding-left:var(--wp--preset--spacing--50)\">Perform the test now<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:20%\"><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer wp-embed-aspect-16-9 wp-has-aspect-ratio\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>What is Wolfram Syndrome (WS)? This extremely rare, genetically determined disease was first described in 1938 by Dr. Hans Wolfram and named after him. Other terms describe the symptoms of the disease: arginine-vasopressin deficiency, diabetes mellitus, optic atrophy, hearing loss syndrome, or DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy, deafness syndrome). Wolfram Syndrome is [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-8833","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/pages\/8833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/comments?post=8833"}],"version-history":[{"count":0,"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/pages\/8833\/revisions"}],"wp:attachment":[{"href":"https:\/\/savir-center.com\/en\/wp-json\/wp\/v2\/media?parent=8833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}